BDBM320286 (2R,6S)-4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(R)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-8-yl]-2,6-dimethylmorpholine::US10174024, Example 3

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2c1)-c1c(C)nnn1C

InChI Key InChIKey=YDERKBMHWDXQGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320286   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320286(US10174024, Example 3 | (2R,6S)-4-[3-(Dimethyl-1H-...)
Affinity DataIC50: 5nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent