BDBM319629 6-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::US10174011, Example 30

SMILES O=C1COc2ccc(CCN3CCN(CC3)c3cccc4sccc34)cc2N1

InChI Key InChIKey=RSDQZKVVYWSUBP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319629   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319629(US10174011, Example 30 | 6-(2-(4-(benzo[b]thiophen...)
Affinity DataEC50:  0.626nMAssay Description:The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319629(US10174011, Example 30 | 6-(2-(4-(benzo[b]thiophen...)
Affinity DataIC50: 34.2nMAssay Description:The D2 receptor antagonism activity test (The antagonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319629(US10174011, Example 30 | 6-(2-(4-(benzo[b]thiophen...)
Affinity DataIC50: 42.1nMAssay Description:The 5-HT2A receptor antagonism activity test (The antagonism activity of test compounds on 5-HT2A receptor expressing human recombinant 5-HT2A recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent