BDBM319591 US10174007, Example 10::US10787438, Example 10::US10988463, Example 10::US11634410, Example 10

SMILES C[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)N1C[C@H]2[C@H](CC(=O)NS(C)(=O)=O)[C@H]2C1

InChI Key InChIKey=YIJQJKBSWSLTEE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 319591   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319591(US10174007, Example 10 | US10787438, Example 10 | ...)
Affinity DataIC50: 682nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319591(US10174007, Example 10 | US10787438, Example 10 | ...)
Affinity DataIC50: 682nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319591(US10174007, Example 10 | US10787438, Example 10 | ...)
Affinity DataIC50: 682nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319591(US10174007, Example 10 | US10787438, Example 10 | ...)
Affinity DataIC50: 682nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent