BDBM31900 Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25.2HCl

SMILES Clc1ccc2c(NCCCCCCNC(=O)CCc3ccc4nc(-c5ccccc5)c5CCCOc5c4c3)c3CCCCc3nc2c1

InChI Key InChIKey=KLGKWPHPNYLNFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31900   

TargetAcetylcholinesterase(Human)
Universitat De Barcelona

LigandPNGBDBM31900(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25....)
Affinity DataIC50: 11.1nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

LigandPNGBDBM31900(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25....)
Affinity DataIC50: 30.8nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

LigandPNGBDBM31900(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25....)
Affinity DataIC50: 218nMAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

LigandPNGBDBM31900(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25....)
Affinity DataIC50: 11nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed