BDBM318929 6-(3-fluoro-2-(2,2,2-trifluoroethoxy)phenyl)-1-methyl-N-((1-methylpiperidin-4-yl)methyl)-1H-indazol-3-amine::US10173985, Example 44

SMILES CN1CCC(CNc2nn(C)c3cc(ccc23)-c2cccc(F)c2OCC(F)(F)F)CC1

InChI Key InChIKey=CFFIHHXSJBUPBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318929   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM318929(US10173985, Example 44 | 6-(3-fluoro-2-(2,2,2-trif...)
Affinity DataIC50: 1.86E+3nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM318929(US10173985, Example 44 | 6-(3-fluoro-2-(2,2,2-trif...)
Affinity DataIC50: 4.50E+3nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent