BDBM318927 6-(2-(2,2-difluoroethoxy)-3-methoxyphenyl)-1-methyl-1H-indazol-3-amine::US10173985, Example 41

SMILES COc1cccc(-c2ccc3c(N)nn(C)c3c2)c1OCC(F)F

InChI Key InChIKey=QKHLTDMSXWVDIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318927   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM318927(US10173985, Example 41 | 6-(2-(2,2-difluoroethoxy)...)
Affinity DataIC50: 1.07E+3nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM318927(US10173985, Example 41 | 6-(2-(2,2-difluoroethoxy)...)
Affinity DataIC50: 3.30E+4nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent