BDBM318437 (2S,4R)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophenyl)prop-2-yn-1-yl)oxy)piperidine-2-carboxylic acid::US9624234, 52

SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)OCC#Cc1ccc(F)cc1

InChI Key InChIKey=CHBCMPSHJIDNQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318437   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318437((2S,4R)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophen...)
Affinity DataIC50: 228nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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