BDBM31804 Apogossypol derivative, 8m

SMILES Cc1cc2c(C(=O)NCC3CCCCC3)c(O)c(O)cc2c(O)c1-c1c(C)cc2c(C(=O)NCC3CCCCC3)c(O)c(O)cc2c1O

InChI Key InChIKey=OQQWENIODLCZHS-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31804   

TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31804(Apogossypol derivative, 8m)
Affinity DataIC50: 1.10E+3nM Kd:  850nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31804(Apogossypol derivative, 8m)
Affinity DataIC50: 710nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31804(Apogossypol derivative, 8m)
Affinity DataIC50: 780nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31804(Apogossypol derivative, 8m)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed