BDBM3180 3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione::5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}pentanimidamide::Bisindolylmaleimide 15::ROCHE screening, 54

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCC(N)=N)c3ccccc23)c2ccccc12

InChI Key InChIKey=XIFBOSNPWOEMFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3180   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 31nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 7.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Technical University of Dortmund

LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 800nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed