BDBM317530 6-chloro-3-[(1S)-1-({1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)ethyl]-1,2-dihydroquinolin-2-one::US9624175, Compound I-45

SMILES C[C@H](Nc1ncc2cn[nH]c2n1)c1cc2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=JYWGNEROAYIITB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317530   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Forma Therapeutics

US Patent
LigandPNGBDBM317530(US9624175, Compound I-45 | 6-chloro-3-[(1S)-1-({1H...)
Affinity DataIC50: 550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

LigandPNGBDBM317530(US9624175, Compound I-45 | 6-chloro-3-[(1S)-1-({1H...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent