BDBM317529 3-[(1S)-1-({1-acetyl-1H,2H,3H-pyrido[3,4-b][1,4]oxazin-5-yl}amino)ethyl]-6-chloro-1,2-dihydroquinolin-2-one::US9624175, Compound I-44

SMILES C[C@H](Nc1nccc2N(CCOc12)C(C)=O)c1cc2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=XJNPVEZQLFGOMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317529   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Forma Therapeutics

US Patent
LigandPNGBDBM317529(US9624175, Compound I-44 | 3-[(1S)-1-({1-acetyl-1H...)
Affinity DataIC50: 5.50E+3nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM317529(US9624175, Compound I-44 | 3-[(1S)-1-({1-acetyl-1H...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent