BDBM31655 CHEMBL179494::imidazole-dioxolane, 7

SMILES Nc1cccc(SC[C@@H]2CO[C@@](CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)c1

InChI Key InChIKey=DQRVOOHZRJYBIQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31655   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 6.00E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 3.20E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed