BDBM31654 CHEMBL368045::imidazole-dioxolane, 6

SMILES Nc1ccccc1SC[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1

InChI Key InChIKey=WOBSVVYLPWQEIY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31654   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50: 4.20E+4nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed