BDBM316169 2-{[3-({4-[3-(2-{2-[2-(dimethylamino)ethoxy]ethoxy}ethyl)ureido]phenyl}ethynyl)-1H-indazol-6-yl]thio}-N-methylbenzamide ::US9617222, Compound 44

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)NCCOCCOCCN(C)C)cc1

InChI Key InChIKey=DWHVITIFAQSODV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316169   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316169(2-{[3-({4-[3-(2-{2-[2-(dimethylamino)ethoxy]ethoxy...)
Affinity DataIC50: 3.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent