BDBM316165 N-{5-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-indazol-3-yl)ethynyl]pyridine-2-yl}-2,5,8,11,14,17-hexaoxanonadecane-19-amide ::US9617222, Compound 40

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)COCCOCCOCCOCCOCCOC)nc1

InChI Key InChIKey=OOUXZAQZDUGVIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316165   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316165(N-{5-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 12nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent