BDBM316160 2-[(3-{[5-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}ureido)pyridine-2-yl]ethynyl}-1H-indazol-6-yl)thio]-N-methylbenzamide ::US9617222, Compound 35

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)NCCOCCOCCOC)cn1

InChI Key InChIKey=JMZMHGYVLUTOOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316160   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316160(2-[(3-{[5-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
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Date in BDB:
5/7/2019
Entry Details
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