BDBM316151 2-({3-[(4-{[2-(2-methoxyethoxy)ethyl]amino}phenyl)ethynyl]-1H-indazol-6-yl}thio)-N-methylbenzamide ::US9617222, Compound 26

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NCCOCCOC)cc1

InChI Key InChIKey=NQIRVVDMPRFORK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316151   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316151(2-({3-[(4-{[2-(2-methoxyethoxy)ethyl]amino}phenyl)...)
Affinity DataIC50: 3.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent