BDBM316144 N-{3-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-indazol-3-yl)ethynyl]phenyl}-2,5,8,11,14,17-hexaoxanonadecane-19-amide ::US9617222, Compound 19

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1cccc(NC(=O)COCCOCCOCCOCCOCCOC)c1

InChI Key InChIKey=UYSZJDSMZJAOQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316144   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316144(N-{3-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.60nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent