BDBM316142 2,5,8,11-tetraoxatridecane-13-yl {4-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-indazol-3-yl)ethynyl]phenyl}carbamate ::US9617222, Compound 17

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)OCCOCCOCCOCCOC)cc1

InChI Key InChIKey=YWQFEXDQIZOYBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316142   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316142(2,5,8,11-tetraoxatridecane-13-yl {4-[(6-{[2-(methy...)
Affinity DataIC50: 6.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent