BDBM315695 (6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetonitrile1H NMR (400 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.93 (d, J = 7.7, 1H), 7.85 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.60 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.4, 2.5, 1H), 7.40 (d, J = 9.1, 1H),7.21 (d, J = 2.4, 1H), 6.72 (d, J = 5.0, 1H), 6.28(d, J = 4.8, 1H), 5.38 (s, 2H), 3.81-3.75 (m,::US10172859, Example 119::US11065253, Example 119::US9732094, Example 119
SMILES OC(c1ccc(OCC#N)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1
InChI Key InChIKey=VMNGDZCHPAYWBU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315695
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair