BDBM315687 US10172859, Example 112::US11065253, Example 112::US9732094, Example 112::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-[6-(2- methoxyethoxy)- pyridazin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.5, 2.5, 1H), 7.25-7.19 (m, 2H),6.61 (d, J = 5.0, 1H), 6.23 (d, J = 5.0, 1H), 4.54-4.50 (m, 2H), 3.80-3.75 (m, 4H), 3.71-3.67(m, 2H), 3.48-3.43 (m, 4H), 3.29 (s, 3H)
SMILES COCCOc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1
InChI Key InChIKey=VEXMWYKCSKRUDC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315687
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair