BDBM315646 (R)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.70 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H), 7.53- 7.50 (m, 2H), 7.42-7.37 (m, 1H), 7.22-7.19 (m, 2H), 6.48 (d, J = 4.4, 1H), 6.02 (d, J = 4.4, 1 H), 4.00 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H)::US10172859, Example 71::US11065253, Example 71::US9732094, Example 71
SMILES COc1ccc(nn1)[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1
InChI Key InChIKey=IDTQOMSFKJPUNB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315646
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair