BDBM31535 pyrazolo[4,3-h]quinazoline-3-carboxamide, 18

SMILES Cn1nc(C(=O)NCCO)c2CCc3cnc(Nc4ccccc4)nc3-c12

InChI Key InChIKey=NXZVLIWBXMLTSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31535   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM31535(pyrazolo[4,3-h]quinazoline-3-carboxamide, 18)
Affinity DataIC50: 74nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM31535(pyrazolo[4,3-h]quinazoline-3-carboxamide, 18)
Affinity DataIC50: 364nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed