BDBM315319 1-Methyl-3-{1-[5- methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3,4-dihydro-1H- quinazolin-2-one::US10172843, Example 53

SMILES CN1C(=O)N(Cc2ccccc12)C1CCN(Cc2nc([nH]c2C)-c2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=ZTWJFDIZJUWRFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315319   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315319(US10172843, Example 53 | 1-Methyl-3-{1-[5- methyl-...)
Affinity DataIC50: 145nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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