BDBM315310 1-{1-[2-(3-Fluoro-4- trifluoromethyl-phenyl)- 5-methyl-1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3-methyl-1,3- dihydro-benzoimidazol- 2-one::US10172843, Example 44

SMILES Cc1[nH]c(nc1CN1CCC(CC1)n1c2ccccc2n(C)c1=O)-c1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=PCOZKVQBVXDCQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315310   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315310(US10172843, Example 44 | 1-{1-[2-(3-Fluoro-4- trif...)
Affinity DataIC50: 385nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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