BDBM315304 3-{1-[5-Methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1H-pyrrolo [2,3- b]pyridine::US10172843, Example 38

SMILES Cc1[nH]c(nc1CN1CCC(CC1)c1c[nH]c2ncccc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HPBAKSVLSBAZDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315304   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315304(US10172843, Example 38 | 3-{1-[5-Methyl-2-(4- trif...)
Affinity DataIC50: 470nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent