BDBM315296 5-Chloro-3-(2-hydroxy-ethyl)-1-{1-[5-methyl-2-(4-trifluoromethyl-phenyl)-1H-imidazol-4-ylmethyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US10172843, Example 30

SMILES Cc1[nH]c(nc1CN1CCC(CC1)n1c2ccc(Cl)cc2n(CCO)c1=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YIDFISCBXAYQHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315296   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315296(US10172843, Example 30 | 5-Chloro-3-(2-hydroxy-eth...)
Affinity DataIC50: 230nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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