BDBM315276 1-{1-[5-Methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-6-morpholin-4-yl- 1,3-dihydro- benzoimidazol-2-one::US10172843, Example 10

SMILES Cc1[nH]c(nc1CN1CCC(CC1)n1c2cc(ccc2[nH]c1=O)N1CCOCC1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YCTGXUZWNWTQJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315276   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315276(US10172843, Example 10 | 1-{1-[5-Methyl-2-(4- trif...)
Affinity DataIC50: 280nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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