BDBM315215 -2-(3-{[2-cyclopentyl-2-{4-[5-chloropyridin-3-yl]phenyl}acetyl]amino}-2-methylphenyl)cyclopropanecarboxylic acid::US10172814, Example 157

SMILES Cc1c(NC(=O)C(C2CCCC2)c2ccc(cc2)-c2cncc(Cl)c2)cccc1C1CC1C(O)=O

InChI Key InChIKey=TZVOLYZIRGQFOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 315215   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM315215(-2-(3-{[2-cyclopentyl-2-{4-[5-chloropyridin-3-yl]p...)
Affinity DataIC50: 29.5nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetProstaglandin E synthase(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM315215(-2-(3-{[2-cyclopentyl-2-{4-[5-chloropyridin-3-yl]p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed