BDBM314866 (R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluorophenyl](cyclopentyl)acetyl}amino)-2-methylphenyl]propanoic acid::US10172814, Example 43

SMILES Cc1c(CCC(O)=O)cccc1NC(=O)C(C1CCCC1)c1ccc(c(F)c1)-c1cncc(Cl)c1

InChI Key InChIKey=OZUBHMWSFYBJDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314866   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM314866((R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluorophe...)
Affinity DataIC50: 30.1nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM314866((R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluorophe...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed