BDBM314862 (R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-methylphenyl](cyclopentyl)acetyl}amino)-2-methylphenyl]propanoic acid::US10172814, Example 42

SMILES Cc1cc(ccc1-c1cncc(Cl)c1)C(C1CCCC1)C(=O)Nc1cccc(CCC(O)=O)c1C

InChI Key InChIKey=GAZFWMPSEBFSJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314862   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM314862((R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-methylphe...)
Affinity DataIC50: 46nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM314862((R/S) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-methylphe...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed