BDBM314687 (2-(pyrimidin-2-yl)phenyl)((1S,3R,4R,6R)-3-methyl-6-((6-fluoro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2.2.1]heptan-2-yl)methanone::US9611262, Example 219

SMILES CC1C2CC(Oc3ccc(c(F)n3)C(F)(F)F)C(C2)N1C(=O)c1ccccc1-c1ncccn1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314687   

TargetOrexin/Hypocretin receptor type 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM314687((2-(pyrimidin-2-yl)phenyl)((1S,3R,4R,6R)-3-methyl-...)
Affinity DataKi:  4nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM314687((2-(pyrimidin-2-yl)phenyl)((1S,3R,4R,6R)-3-methyl-...)
Affinity DataKi:  1.01E+3nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent