BDBM314391 US9611249, Compound 25::US9611249, Compound 25b::{4-[({[5-(Pyrimidin-5-yl)-1H-indazol-3- yl]carbonyl}amino)methyl]piperidin-1- yl}acetic acid hydrate

SMILES OC(=O)CN1CCC(CNC(=O)c2n[nH]c3ccc(cc23)-c2cncnc2)CC1

InChI Key InChIKey=NPFMAFJDGXNHOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314391   

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314391({4-[({[5-(Pyrimidin-5-yl)-1H-indazol-3- yl]carbony...)
Affinity DataIC50: 220nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314391({4-[({[5-(Pyrimidin-5-yl)-1H-indazol-3- yl]carbony...)
Affinity DataIC50: 530nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent