BDBM314348 (S)-N-{(S)-1-[2-Methoxy-5-(propane-1-sulfonylaminocarbonyl)-naphthalen-1-ylmethyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-2-methylamino-propionamide hydrochloride::US9611224, Example 52b

SMILES CCCS(=O)(=O)NC(=O)c1cccc2c(CN3c4ccccc4CC[C@H](NC(=O)[C@H](C)NC)C3=O)c(OC)ccc12

InChI Key InChIKey=REQYCTGDIZBDQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314348   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM314348(US9611224, Example 52b | (S)-N-{(S)-1-[2-Methoxy-5...)
Affinity DataIC50: 39nMAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM314348(US9611224, Example 52b | (S)-N-{(S)-1-[2-Methoxy-5...)
Affinity DataIC50: 5.48E+4nMAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent