BDBM313685 (S)-N-(3-(6-((2- hydroxypropyl)amino)- 5-(tetrahydro-2H-pyran- 4-yl)pyridazin-3-yl)-4- methylphenyl)-2- (trifluoromethyl) isonicotinamide::US10167279, Example 311

SMILES C[C@H](O)CNc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=RORGLLVNFZEJNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313685   

LigandPNGBDBM313685(US10167279, Example 311 | (S)-N-(3-(6-((2- hydroxy...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent