BDBM313681 N-(3-(6-((2-methoxyethyl)amino)-5-(tetrahydro-2H-pyran-4-yl)pyridazin-3-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide::US10167279, Example 307

SMILES COCCNc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=OWFDORFLXBEOGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313681   

LigandPNGBDBM313681(US10167279, Example 307 | N-(3-(6-((2-methoxyethyl...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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