BDBM313652 (R)-4-chloro-N-(3-(2- (2,3- dihydroxypropoxy)-6- (tetrahydro-2H-pyran-4- yl)pyridin-4-yl)-4- methylphenyl) picolinamide::US10167279, Example 278

SMILES Cc1ccc(NC(=O)c2cc(Cl)ccn2)cc1-c1cc(OC[C@H](O)CO)nc(c1)C1CCOCC1

InChI Key InChIKey=ZLQQYYIUWZJNGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313652   

LigandPNGBDBM313652(US10167279, Example 278 | (R)-4-chloro-N-(3-(2- (2...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent