BDBM313644 2-(2-cyanopropan-2-yl)- N-(3-(2-(2- hydroxyethoxy)-6- (tetrahydro-2H-pyran-4- yl)pyridin-4-yl)-4- methylphenyl) isonicotinamide::US10167279, Example 270

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(C)(C)C#N)cc1-c1cc(OCCO)nc(c1)C1CCOCC1

InChI Key InChIKey=WWVVPXRLAMVCBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313644   

LigandPNGBDBM313644(US10167279, Example 270 | 2-(2-cyanopropan-2-yl)- ...)
Affinity DataIC50: 90nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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