BDBM313580 N-(3-(2- (hydroxymethyl)-2- methyl-3-oxo-8- (tetrahydro-2H- pyran-4-yl)-3,4-dihydro- 2H- benzo[b][1,4]oxazin-6- yl)-4-methylphenyl)-5- (trifluoromethyl) pyridazine-3-carboxamide::US10167279, Example 204

SMILES Cc1ccc(NC(=O)c2cc(cnn2)C(F)(F)F)cc1-c1cc2NC(=O)C(C)(CO)Oc2c(c1)C1CCOCC1

InChI Key InChIKey=FJKDWRMOEUEOSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313580   

LigandPNGBDBM313580(N-(3-(2- (hydroxymethyl)-2- methyl-3-oxo-8- (tetra...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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