BDBM313571 N-(3-(2- (hydroxymethyl)- 2-methyl-3-oxo-5- (tetrahydro-2H-pyran-4- yl)-3,4-dihydro-2H-benzo [b][1,4]oxazin-7-yl)-4- methylphenyl)-5- (trifluoromethyl) pyridazine-3-carboxamide::US10167279, Example 195

SMILES Cc1ccc(NC(=O)c2cc(cnn2)C(F)(F)F)cc1-c1cc2OC(C)(CO)C(=O)Nc2c(c1)C1CCOCC1

InChI Key InChIKey=TWLVHIUKTDMFSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313571   

LigandPNGBDBM313571(N-(3-(2- (hydroxymethyl)- 2-methyl-3-oxo-5- (tetra...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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