BDBM313568 N-(3-(2- (hydroxymethyl)- 2-methyl-3-oxo-5- (tetrahydro-2H-pyran-4- yl)-3,4-dihydro-2H-benzo [b][1,4]oxazin-7-yl)-4- methylphenyl)-4- (trifluoromethyl) picolinamide::US10167279, Example 192::US10167279, Example 193::US10167279, Example 194

SMILES Cc1ccc(NC(=O)c2cc(ccn2)C(F)(F)F)cc1-c1cc2OC(C)(CO)C(=O)Nc2c(c1)C1CCOCC1

InChI Key InChIKey=CVCWPOXZQKWUDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313568   

LigandPNGBDBM313568(US10167279, Example 194 | US10167279, Example 193 ...)
Affinity DataIC50: 300nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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LigandPNGBDBM313568(US10167279, Example 194 | US10167279, Example 193 ...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

LigandPNGBDBM313568(US10167279, Example 194 | US10167279, Example 193 ...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent