BDBM313445 US10167270, Example 142

SMILES Nc1ccc(cc1)-c1nc(NC2Cc3ccccc3C2)c2ccccc2n1

InChI Key InChIKey=XGHROEWWVNJOLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313445   

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313445(US10167270, Example 142)
Affinity DataIC50: 7.10nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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