BDBM313396 N-(6'-ethoxy-2-methyl- 5'-(3-methyloxetan-3- yl)-[3,3'-bipyridin]-5- yl)-2- (trifluoromethyl)isonicotin- amide::US10167279, Example 63

SMILES CCOc1ncc(cc1C1(C)COC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)cnc1C

InChI Key InChIKey=MLGNXKIPPIXQET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313396   

LigandPNGBDBM313396(N-(6'-ethoxy-2-methyl- 5'-(3-methyloxetan-3- yl)-[...)
Affinity DataIC50: 183nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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LigandPNGBDBM313396(N-(6'-ethoxy-2-methyl- 5'-(3-methyloxetan-3- yl)-[...)
Affinity DataIC50: 613nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent