BDBM313305 US10167270, Example 84

SMILES CN([C@H]1CCc2ccccc2C1)c1nc(nc2ccccc12)-c1cccnc1

InChI Key InChIKey=VQHVGTSGQUJEJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313305   

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313305(US10167270, Example 84)
Affinity DataIC50: 500nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313305(US10167270, Example 84)
Affinity DataIC50: 430nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed