BDBM313180 4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl))-2-methoxybenzamide ::US10167256, Compound 102::US10259786, Compound 102

SMILES CCN1CCCC1CNC(=O)c1cc(c(NC)cc1OC)S(=O)(=O)CC

InChI Key InChIKey=NXKXZXNNWRYXRE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 313180   

TargetD(2) dopamine receptor(Human)
Lb Pharmaceuticals

US Patent
LigandPNGBDBM313180(4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...)
Affinity DataIC50: 8.90nMAssay Description:The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Lb Pharmaceuticals

US Patent
LigandPNGBDBM313180(4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...)
Affinity DataIC50: 8.20nMAssay Description:The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Lb Pharmaceuticals

US Patent
LigandPNGBDBM313180(4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...)
Affinity DataIC50: 8.90nMAssay Description:The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Lb Pharmaceuticals

US Patent
LigandPNGBDBM313180(4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...)
Affinity DataIC50: 8.20nMAssay Description:The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent