BDBM312868 6-cyclopropyl-1-[3-[2-[(3R)- 3-hydroxy-1-methyl-2-oxo- pyrrolidin-3-yl]ethynyl] phenyl]pyrazolo[3,4-d]pyri- midine-3-carboxamide::US9605005, Example 158

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cnc(nc23)C2CC2)C1=O

InChI Key InChIKey=UCLXYFFOKZLIKU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312868   

LigandPNGBDBM312868(US9605005, Example 158 | 6-cyclopropyl-1-[3-[2-[(3...)
Affinity DataKi:  0.230nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent