BDBM312840 4-(cyclopropylamino)-1-[3- [2-[(3R)-3-hydroxy-1-meth- yl-2-oxo-pyrrolidin-3-yl]eth- ynyl]phenyl]pyrazolo[4,3- c]pyridine-3-carboxamide::US9605005, Example 130

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3c(NC4CC4)nccc23)C1=O

InChI Key InChIKey=UMNOVBSWYKEADA-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312840   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Genentech

US Patent

LigandBDBM312840(US9605005, Example 130 | 4-(cyclopropylamino)-1-[3...)Copy SMILESCopy InChI

Affinity DataKi:  0.110nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/24/2019
Entry Details
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