BDBM312808 1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]phenyl]-7-methoxy- imidazo[1,5-a]pyridine- 3-carboxamide::US10550117, Compound C-4::US9605005, Example 97

SMILES COc1ccn2c(nc(-c3cccc(c3)C#C[C@]3(O)CCN(C)C3=O)c2c1)C(N)=O

InChI Key InChIKey=PGXYZFMFSWREGO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312808   

LigandPNGBDBM312808(US9605005, Example 97 | 1-[3-[2-[(3R)-3-hydroxy-1-...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

LigandPNGBDBM312808(US9605005, Example 97 | 1-[3-[2-[(3R)-3-hydroxy-1-...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent