BDBM31280 Chalcone derivative, G

SMILES CCOc1ccc(NC(=O)CC(=Nc2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=WHAMZFYDMJTIKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31280   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Max Planck Institute

LigandPNGBDBM31280(Chalcone derivative, G)
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2009
Entry Details Article
PubMed