BDBM31270 CHEMBL360141::isoindolinone scaffold, 65

SMILES CC(=O)NCCN1C(=O)c2ccccc2C1(OCc1ccc(cc1)C(C)(C)C)c1ccccc1

InChI Key InChIKey=BTICYABAFSUXAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31270   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Newcastle Upon Tyne

LigandPNGBDBM31270(CHEMBL360141 | isoindolinone scaffold, 65)
Affinity DataIC50: 1.44E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2009
Entry Details Article
PubMed